Dr. Bowen Xie "The role of the AIM2 Inflammasome in Detering Myogenic Potential of Muscle Satellite Cells in PAD" and Dr. Ed Oh "Wearable Monitoring Devices in Patients with Lower Extremity Bypasses: Improving patency rates"

Dr. Bowen Xie, MD

Title: "The role of the AIM2 Inflammasome in Detering Myogenic Potential of Muscle Satellite Cells in PAD and the Effects of SARS-related Proteins on Potentiating Myopathy"

These projects aimed to evaluate the role of the AIM2 as a mediate of damage of PAD-affected muscle satellite cells and whether it may serve as a potential target to reduce PAD-associated myopathy. We also aimed to explore the the interaction and effects of SARS-related proteins on myoblasts in PAD patients during the COVID-19 pandemic and evaluate the effects of the associated hypercoagulable state on limb loss rates.

Mentor: Ulka Sachdev, MD

Dr. Ed Oh, MD
Title: "Wearable Monitoring Devices in Patients with Lower Extremity Bypasses: Improving patency rates and clinical outcomes"
Wearable technology has been a proven adjunct in the field of cardiology in monitoring arrhythmias and early detection of cardiac pathology.  The aim of this talk is to make a case for the development of monitoring devices in vascular surgery.  While there are multiple use cases including carotid disease, dialysis access maintenance and aortic aneurysm disease, there exists a specific clinical need amongst patients with peripheral vascular disease (PVD) and lower extremity bypasses.  
Mentors: Drs. Edith Tzeng, Mohammad Eslami, Alan Hirschman, Ramakrishna Mukkamala