Determinants of Responses to Total Neoadjuvant Therapy in Rectal Cancer
Presenter: Sowmya Narayanan, MD, PhD (mentor: Jennifer M. Holder-Murray, MD, FACS)
Simmons Research Conferences
Investigating Immune Defects of Aging and Potential Therapies
Presenter: Maryam Mohammed, MD (mentor: Brian Zuckerbraun, MD)
Clinical Trials and Neonates
Presenter: Elizabeth Pace, MD
Safety and Early Biological Activity of Regulatory Dendritic Cell Therapy in Liver Transplantation: Updates from a Phase I/II Clinical Trial
Presenter: Lillian Tran, MD (mentors: Drs. Angus Thomson and Abhi Humar)
Cellular RNA-Regulated Innate Immune Activation in Endothelial Cells
Presenter: Qingde Wang, MD, PhD
Past, Present, and Future of Designing a Novel Small Caliber Synthetic Vascular Graft - Transitioning from Bench to Animal
Presenter: JB Moses, MD
Peripheral artery disease is a growing problem with significant economic impact. Current synthetic bypass grafts offer poor long-term patency for distal small vessel disease defined as less than 6mm in diameter. From idea to prototype, Dr. Moses will be discussing his group's most recent prototypes and the shift from bench to animal models. He will again briefly discuss a more recent project aimed at evaluating best medical management versus surgical management for patients with claudication.
Elevated Carcinoembryonic Antigen Warrants Adjuvant Chemotherapy in High-risk Stage II Colon Cancer
Presenter: Tanner Wilson, MD
Academic Surgical Congress Practice Presentations
Presenters: Drs. Sidrah Khan, Tanner Wilson, Elizabeth Andraska, Jillian Bonaroti, and JB Moses
Cyclic GMP-AMP Synthase Contributes to Epithelial Homeostasis in Intestinal Inflammation Via Beclin-1 Mediated Autophagy / The Effect of NETs in Awakening Dormant Cancer Cells in the Tumor Microenvironment / The Effect of Simultaneous iNOS and COX2...
Cyclic GMP-AMP Synthase Contributes to Epithelial Homeostasis in Intestinal Inflammation Via Beclin-1 Mediated Autophagy
cGAS maintains intestinal epithelial homeostasis during human IBD and murine colitis by upregulating Beclin-1 mediated autophagy and preventing IEC death. Rescue of autophagy can attenuate the severity of colitis associated with cGAS deficiency.
Presenters: Dr. Sidrah Khan (advisor: Dr. Kevin Mollen)
Inflammasome-Mediated Effects of SARS-related proteins on Muscle Satellite Cells in Peripheral Arterial Disease
Presenter: Dr. Bowen Xie (mentor: Ulka Sachdev, MD)
This project aimed to evaluate whether peripheral arterial disease (PAD) potentiates the interaction and effects of SARS-related proteins in myoblasts, as well as the effects of these viral peptides on inflammasome function in PAD patients.